What If Your Antidepressant Isn’t Enough?

If you’ve tried antidepressants but still don’t feel like yourself, you’re not alone.

Many people with treatment-resistant depression have tried multiple medications, only to continue struggling with sadness, low energy, lack of motivation, or feeling emotionally “stuck.”

The good news? There are newer treatment options.

What Is Spravato®?

Spravato® (esketamine) is an FDA-approved nasal spray used to treat adults with treatment-resistant depression. Unlike traditional antidepressants that work on serotonin, Spravato targets a different pathway in the brain called glutamate, helping restore communication between brain cells.

For some people, it may begin working faster than traditional antidepressants.

What Happens During Treatment?

Spravato is given in a certified medical office—not at home.

Your visit is simple:

You self-administer the nasal spray under medical supervision.
Relax in a comfortable treatment room for about two hours while we monitor you.
Have someone drive you home afterward.

Most patients start with two treatments each week before transitioning to a maintenance schedule.

Is Spravato Right for You?

Spravato may be an option if you:

Have tried two or more antidepressants without enough improvement
Continue to struggle with depression despite treatment
Are looking for an alternative approach to managing depression

A psychiatric evaluation is the best way to determine whether Spravato is right for you.

We’re Here to Help

At AG Psychiatry, we provide Spravato treatment in Little Elm, Texas, and care for patients from Frisco, Prosper, Celina, Aubrey, McKinney, The Colony, and surrounding communities.

If depression continues to affect your daily life despite medication, you don’t have to keep wondering what comes next. A different treatment approach may make all the difference.

Schedule a consultation today to learn whether Spravato is the right option for you.

Frequently Asked Questions

How long does a Spravato appointment take?
Plan to be in the office for about two hours so we can monitor you after treatment.

Does insurance cover Spravato?
Many commercial insurance plans and Medicare cover Spravato for eligible patients. Our team can help verify your benefits.

How is Spravato different from ketamine?
Spravato contains esketamine, an FDA-approved medication specifically studied for certain forms of depression and administered under medical supervision through a certified program.